MidAtlantic Bioinformatics Conference 2019

Multi-omics Data Integration for Biomedical Discovery:

Statistical and Machine Learning Approaches to Big Data

Multi-omics Data Integration for Biomedical Discovery:

Statistical and Machine Learning Approaches to Big Data

REGISTRATION FOR THIS CONFERENCE IS CLOSED
WE HAVE REACHED CAPACITY

What

MidAtlantic Bioinformatics Conference 2019

When

Friday October 11, 2019

Where

Convene Cira Centre

2900 Arch Street

Philadelphia, PA 19104

Contact Us

To learn more, don’t hesitate to get in touch

Presented by

The Department of Biomedical and Health Informatics at Children's Hospital of Philadelphia &

University of Pennsylvania's Institute for Biomedical Informatics

Fourth Annual

10/11/2019

PHILADELPHIA

 

The Speakers

Jinghui Zhang, PhD

Chair of the Department of Computational Biology

St. Jude Endowed Chair in Bioinformatics

St. Jude Children’s Research Hospital

KEYNOTE SPEAKER

Dr. Zhang is a computational biologist focused on the integrative analysis of large-scale, multi-dimensional genomic data to understand the initiation and progression of diseases. Her research interest has been in the development of highly accurate and sensitive computational methods for analyzing arge-scale genomic data, especially in the area of detecting and analyzing genetic variations and somatic mutations. Most recently her team developed a suite of algorithms for discovery of structural variations and copy number alterations in cancer genome at high accuracy. Dr. Zhang developed mathematical models for mapping clonal evolution trajectory from diagnosis to relapse for pediatric solid tumor and leukemia and has led major studies that have examined the nature of inherited genetic variants in both human and mouse genomes including describing single nucleotide variants in one of the first sequenced human genomes and prevalence of germline mutations causing cancer susceptibility in >1000 children with cancer. She earned her undergraduate degree from Fu Dan University, Shanghai, China and her Master’s and PhD from the University of Connecticut.

Lior Pachter, PhD

Bren Professor of Computational Biology 

California Institute of Technology

Professor Pachter is a computational biologist working in genomics. His career began in comparative genomics, and initially was interested in genome alignment, annotation, and the determination of conserved regions using phylogenetic methods. More recently he's become focused on functional genomics, which includes answering questions about the function and interaction of DNA, RNA and protein products. He's particularly interested in applications of high-throughput sequencing to RNA biology. Genomics requires the development of algorithms, statistical methodology and mathematical foundations, and a major part of his research is therefore on methods. Dr. Pachter earned his undergraduate degree at California Institute of Technology and his PhD from Massachusetts Institute of Technology.

KEYNOTE SPEAKER

Bruce Aronow, PhD

Professor,  Department of Pediatrics

University of Cincinnati

Co-director, Computational Medicine Center

Cincinnati Children’s Hospital

Elana Fertig, PhD

Associate Professor of Oncology

Assistant Director of the Research Program in Quantitative Sciences

Johns Hopkins University

Lana Garmire, PhD

Associate Professor

Faculty Director of Bioinformatics Core

University of Michigan

Associate Professor,Systems Pharmacology

and Translational Therapeutics

University of Pennsylvania

Casey Greene, PhD

Jason Moore, PhD

Edward Rose, MD and Elizabeth

Kirk Rose, MD Professor

Director, Institute for Biomedical Informatics

University of Pennsylvania

Tuuli Lappalainen, PhD

Assistant Professor, Department of Systems Biology, Columbia University
Junior Investigator and Core Member,

New York Genome Center

 

Multi-omics Data Integration for Biomedical Discovery:

Statistical and Machine Learning Approaches to Big Data

7:30

Registration & Continental Breakfast

8:15

Welcome  

Bryan Wolf, MD 

CSO, Children's Hospital of Philadelphia

8:30

Keynote - Jinghui Zhang, PhD

GENOMIC VARIANTS IN PEDIATRIC CANCER

9:30

Lana Garmire, PhD

MULTI-OMICS DATA BASED PATIENT SURVIVAL PREDICTION WITH DEEP-LEARNING

10:00

Jason Moore, PhD

ACCESSIBLE ARTIFICIAL INTELLIGENCE FOR GENOMIC ANALYSIS

10:30

Morning Break

10:45

Elana Fertig, PhD

TRANSFER LEARNING FOR CROSS-SPECIES, CROSS-TISSUES, AND SPATIAL SINGLE CELL ANALYSIS

11:15

Poster Lightning Round

Ruchi Lohia,  Rutgers University

Zhen Miao, University of Pennsylvania

Yang Pan, PhD  Children's Hospital of Philadelphia/UCLA

Jinchaun Xing, PhD  Rutgers University

Jinli Zhang, PhD  Drexel University/Beijing University of Technology

11:45

Lunch & Poster Session

2:00

Keynote 2- Lior Pacher, PhD

METHODS FOR INTERPRETING PERTURBATION EXPERIMENTS IN THE CONTEXT OF CELL ATLASES

Casey Greene, PhD

ML-BASED ANALYSES OF RARE DISEASES ARE ENHANCED BY TRAINING MODELS ON PUBLIC DATA COMPENDIA

Agenda

3:00

3:30

Afternoon Break

3:45

Tuuli Lappalainen, PhD

THE GTEX CONSORTIUM ATLAS OF GENETIC REGULATORY EFFECTS ACROSS HUMAN TISSUES

4:15

Bruce Aronow, PhD

USING SYSTEMS BIOLOGY TO TRANSLATE FROM SINGLE CELL GENOMICS TO NEXT GENERATION PRECISION MEDICINE

4:45

Closing

 

Convene Cira Centre

2900 Arch Street

Philadelphia, PA 19104

Location

Convene Cira Conference Centre is conveniently located next to Philadelphia’s 30th Street Station

close to the research campus of the Children’s Hospital of Philadelphia and the University of Pennsylvania.

Convene Cira Conference Center is accessible via public transportation or rideshare. It is connected to the 30th Street Station, where the Amtrak, Regional Rail and the Subway lines intersect. Parking is available in the Cira garage. A 5$ parking discount voucher will be available.

 

Directions

 

Call for Posters

Authors are invited to submit posters on algorithm, software, database, and

analysis of genetic or genomic data, including but not limited to following topics:

 

  • Integrative Analyses of Biological Data on Multiple Scales       

  • Diagnostic Focus on Genetic and Genomic Data

  • Machine Learning Methods Applied to Single- and Multi-level ‘omics’ Data    

  • Structural Variants and Non-coding Variants

  • Visualization and Visual Analytics of Biological and Health Data         

  • Epigenetics of Human Diseases

  • Computational Systems Biology and Biological Network Modeling     

  • Epistasis of Genetic Variants

  • Population and Comparative Genomics                                   

  • Single-cell Sequencing and Analyses

  • Translational Bioinformatics                                                  

  • Imputation of Genomic and Epigenomic Data

  • Genome and Sequence Analysis                                             

  • Bioinformatics Methods Development

  • Genotype-Phenotype Relationships                     

 

New in 2019: Poster Lightning Round
 
Poster selection is complete. Thanks to all who submitted. 

Conference Committee

Conference Chair

Yi Xing, PhD

Professor of Pathology and Laboratory Medicine

Perelman School of Medicine at the University of Pennsylvania

 

Conference Co-Chair

Deanne Taylor, PhD

Research Assistant Professor

Perelman School of Medicine at the University of Pennsylvania

 

Committee Members

Laura Almasy, PhD

Professor, Genetics

University of Pennsylvania

 

Kai Tan, PhD

Associate Professor of Pediatrics, Genetics, and Cell and Developmental Biology

Children's Hospital of Philadelphia

 

Kai Wang, PhD

Associate Professor of Pathology and Laboratory Medicine

Perelman School of Medicine at the University of Pennsylvania

Children's Hospital of Philadelphia

 

Logistics and Operations

CHOP Department of Biomedical & Health Informatics

Colleen Gaynor

Hannah Lazarus

Mark Diltz

Donna Vito